If we combine this info using your safeguarded health and fitness info, We'll address all of that information and facts as secured overall health data and will only use or disclose that information as established forth in our notice of privateness practices. You could possibly choose-from electronic mail communications at any time by clicking about the unsubscribe backlink from the e-mail.

Right before having this medication, inform your medical professional or pharmacist Should you be allergic to promethazine or to dextromethorphan; or to almost every other phenothiazines (such as prochlorperazine); or Should you have any other allergies.

Explain to your health care provider if you are pregnant or think you could be pregnant. Through pregnancy, this item is not proposed. It may well damage an unborn child. Speak to your health practitioner concerning the threats and benefits of this medication. See also Warning portion.

This medication may bring about harm and Demise if it is taken by other Older people, youngsters, or pets. It can be crucial to remove the medication as soon as you not will need it or it can be expired. You can do this in two ways:

Physical dependence, the affliction during which continued administration of your drug is necessary to stop the looks of a withdrawal syndrome, assumes clinically substantial proportions only after several weeks of ongoing oral opioid use, although some delicate diploma of Actual physical dependence may well build immediately after a few days of opioid therapy.

Discuss with your treatment staff about naloxone and how to get it. Naloxone is really an emergency medication useful for an opioid overdose. An overdose can materialize if you're taking an excessive amount opioid. It might also materialize if an opioid is taken with Various other remedies or substances, like Liquor.

, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer which include rifampin, carbamazepine, and phenytoin, may well lead to a rise in codeine plasma concentrations with subsequently higher metabolism by cytochrome P450 2D6, leading to greater morphine amounts, which could increase or extend adverse reactions and could induce possibly fatal respiratory melancholy.

A lot of the studies, each optimistic and damaging, were limited by compact sample measurement, remember bias and lack of data pertaining to dose and timing of publicity.

Promethazine HCl and Codeine Phosphate Oral Remedy ought to be used with warning in patients with bone- marrow melancholy. Leukopenia and agranulocytosis happen to be noted, commonly when promethazine has long been used in association with other recognized marrow-poisonous agents.

A family teaspoon is not an exact measuring machine and could lead to overdosage, particularly when 50 % a teaspoon will be to be calculated. It's strongly suggested that an precise measuring system be Promethazine codeine syrup utilised. A pharmacist can offer an correct product and can offer Guidelines for measuring the correct dose.

g., amiodarone, quinidine) may possibly end in an increase in codeine plasma concentrations in addition to a reduce in active metabolite morphine plasma focus which could lead to an analgesic efficacy reduction or signs of opioid withdrawal.

Having said that, this outcome is just not dependable and may be offset by an elevated level of cervical dilation, which tends to shorten labor. Watch neonates exposed to opioids throughout labor for indications of excessive sedation and respiratory depression.

Codeine has fantastic antitussive exercise, While fewer than that of morphine at equal doses. It can be Utilized in desire to morphine, because Unwanted effects are infrequent at the same old antitussive dose of codeine.

As well as its desired outcomes, a medication may bring about some unwanted outcomes. Even though not these Negative effects could arise, should they do manifest They might have to have healthcare awareness.